CellCards: An Integrative System of Cell Cards
CellCards is a web program that collects, annotates, and provides two types of cell cards: (i) Cards of individual cell types, such as podocyte, and (ii) Cards of cell connectomes. A cell connectome is a group of cell types that collectively form a functional unit such as the Renin-Angiotensin-Aldosterone System (RAAS).
Cards of Cell Types:
With intensive cell research, it is desired to integrate knowledge and data for individual cell types. Examples include:
- Juxtaglomerular cell
- T cell
Cards of Cell Connectomes:
Two general types of cell connectomes are represented: (i) Connectomes of cells that are in direct or proximate contact and work together as a functional unit, and (ii) Connectomes of cells that functionally connected via networks of messaging molecules such as hormones and cytokines. Examples include:
- RAAS cell connectome
- Kidney juxtaglomerular apparatus cell connectome for monitoring bodily sodium levels and secreting renin
- Cell connectome of the intestinal crypts
- Cell connectome of the Peyer's patch
- Cytokine storm cell connectome. Note: Cytokine storm occurs as a result of a disease such as an infection (e.g., COVID-19) or autoimmune disease, or occur after a medical intervention such as immunotherapy. How cells are collectively involved in cytokine storm under different scenarios is still unclear.
Note: Currently under development. Feedback is welcome. Thanks!